Pablo de León was born in Portugal and moved to Brazil at the age six, when he began playing the violin. He won a scholarship to study violin in Israel with the renowned violinist and teacher Chaim Taub.

León has been a featured soloist with many Brazilian and European orchestras, including the Amazonas Filarmônica , Orquestra Sinfônica Municipal de São Paulo, Orquestra Sinfônica Brasileira (Rio de Janeiro), Orquestra Sinfônica do Teatro Nacional Cláudio Santoro (Brasília), Orquestra Sinfônica de Campinas, Academic Orchestra of Madrid, among many others.

In Brazil he holds the important roll as a chamber musician, having played with artists such as: Regis Pasquier, Isabelle van Keullen, Hagai Shaham, Roi Shiloah, Reiner Kuchl and Guy Braunstein. He has played chamber music concerts for CNN and BBC Radio in London. 

Since 2003 Pablo de León is the only Brazilian violinist  playing in the World Orchestra for Peace where the musicians are the leading concertmaster and principals in the most prestigious orchestras around the world, under the baton of Valery Gergiev. Having already played in Moscow, St. Petersburg, Beijing, Berlin, Rotterdam, London, Budapest, Jerusalem, Brussels, Krakow, Stockholm, Abu Dhabi, Salzburg, New York and Chicago. Highlight for the 2012 tour, where he was concertmaster at Carnegie Hall in New York and Symphony Hall in Chicago.

As a violin teacher, he taught at several festivals in Brazil, such as the Eleazar de Carvalho Festival in Fortaleza, Campos do Jordão International Festival, Brasília International Summer Festival, Festival Música nas Montanhas in Poços de Caldas, among others. He played a recital and gave master classes at the Jascha Heifetz Symposium of Individual Style (New London- United States), where León with his unique sound and technique impressed Sherry Kloss (former student of Heiftez) who compared him to the refined violinist Franco Gulli.  

Pablo de León was the concertmaster in the  Orquestra Sinfônica Brasileira (Brazilian Symphonic Orchestra of Rio de Janeiro) from 2008 to 2014. Since 2000 he has been concertmaster  of the Orquestra Sinfônica Municipal de São Paulo (Symphonic Orchestra of São Paulo).